Fulham have picked up just four points from 42 available in Premier League away games against Manchester United (W1 D1 L12), winning 3-1 in October 2003 and drawing 2-2 in February 2014.
Leeds are looking to complete their first league double over Southampton since 2005-06 (in the EFL Championship), while they last did the Premier League double against Saints in 2001-02.
Chelsea are winless in their last six Premier League meetings with Leicester (D4 L2), having won nine of their previous 11 against them in the competition (D1 L1).
Wolves have won just one of their last nine away league games against Everton (D3 L5), winning 3-1 in February 2019.
Newcastle have lost their final home league game in each of the last two seasons, having won five in a row beforehand. They last lost more such games consecutively with a run of three between 2006-07 and 2008-09.
Tottenham have won 11 of their last 12 Premier League home games played on Wednesdays (D1) since a 0-1 defeat against Leicester City in January 2016.
Crystal Palace striker Christian Benteke has been involved in seven goals in 14 Premier League appearances against Arsenal (4 goals, 3 assists) – only against Chelsea (9) and Sunderland (8) has he been involved in more in the competition.
Ashley Barnes scored the winner for Burnley against Liverpool at Anfield this season. The last player to score home and away against them for the Clarets in the same league season was Willie Irvine in 1965-66.
