Australia's only current UFC champion, Alex Volkanovski, will return to the octagon on Sunday 26th September (AEST), when he defends his featherweight title against Brian Ortega.
Volkanovski hasn't fought since July last year, where he successfully defended his title against Max Holloway at UFC 251.
In the co-main, Valentina Shevchenko will defend her women's flyweight title against Lauren Murphy.
Here's everything you need to know about UFC 266.
WHEN IS UFC 266?
UFC 266 will take place on Sunday 26th September (AEST), which is of course Saturday night in the US.
The event will emanate live from T-Mobile Arena in Las Vegas, Nevada.
The pay-per-view portion of the show will begin at midday.
WHAT TIME IS UFC 266 IN AUSTRALIA?
UFC 266 will begin at midday AEST for the pay-per-view portion of the event.
The early prelims will begin at 8am and run for two hours, with the prelims to begin at 10am and run for two hours as well.
HOW TO WATCH OR STREAM UFC 266 IN AUSTRALIA
As with all UFC pay-per-view events, you can catch them live on Main Event for $54.95.
You can also watch the event live and in full on Kayo Sports.
UFC 266 FIGHT CARD
Two title fights will headline with UFC 266 card, with Australia's Alex Volkanovski defending his strap against Brian Ortega, while women's flyweight stars Valentina Shevchenko and Lauren Murphy go head-to-head.
Nick Diaz will step inside the octagon for the first time since 2015, taking on former welterweight champion Robbie Lawler.
Here's the full card for UFC 266.
UFC 266 Main Card
- UFC Featherweight Title: Alex Volkanovski (c) vs Brian Ortega
- UFC Women's Flyweight Title: Valentina Shevchenko (c) vs Lauren Murphy
- Nick Diaz vs Robbie Lawler
- Curtis Blaydes vs Jairzinho Rozenstruik
- Jessica Andrade vs Cynthia Calvillo
UFC 266 Prelim Card
- Marlon Moraes vs Merab Dvalishvili
- Dan Hooker vs Nasprat Haqparast
- Shamil Abdurakhimov vs Chris Daukas
UFC 266 Early Prelim Card
- Manon Fiorot vs Mayra Bueno Silva
- Karl Roberson vs Nick Maximov
- Matthew Semelsberger vs Martin Sano
'Fuel to the fire' - Dan Hooker fighting for Fau Vake at UFC 266
Dan Hooker is pissed off. He has every reason to be.
In May, Hooker's training partner and good friend, Fau Vake, was attacked by four men while on a night out in Auckland.
The cowardly attack left Fau fighting for his life in Auckland City Hospital. He died nine days later.
In August, one of the men involved in the attack was sentenced. Prosecutors allege Ofa Folau was involved in the early part of the attack, but wasn't considered responsible for Fau's death.
He was sentenced to just six months home detention.
So yeah, Dan Hooker is pissed off.
"I'm angry about the situation, and that's definitely fuelled my training," Hooker told Sporting News ahead of his bout with Nasrat Haqparast at UFC 266 on September 25 (September 26 in Australia).
"It's fuelled my thirst to get out there and fight. I have always have that thirst, but it's definitely added an incredible amount of fuel to the fire.
"There's a lot of anger about the situation - a lot of emotion - and the only way that I know how to deal with that kind of emotion is to fight, to get out there and compete."
Click here for our full story on Dan Hooker ahead of his UFC 266 fight.